See the repository above. Yeah, its possible, he told mehe also says that he has regularly seen Kirsch manipulate evidence so that it seems to support claims that are, in reality, baseless. There is absolutely no evidence that either one of these claims is true, as Morris has carefully documented. Twenty-four years ago, . This looks ominous, but it harmless. Doctors who have used fluvoxamine in the US and other countries swear by it. How covid-19 conspiracy videos keep getting millions of views. Mouse Systems is not a household word, he told the journalist. Steve Kirsch -Executive Director at COVID-19 Early Treatment Fund Ivermection study - One .2mg/kg dose a week for prevention "100% success rate whereas those doctors taking placebo had a 59%% infection rate not a typo 237 of 400 docs on placebo got infected vs. 800 docs on Ivermectin none got infected" Antivirals Completely avoid caffeine, alcohol, tylenol, and benadryl. He is the inventor of the optical mouse and one of the first Internet search engines, Infoseek. thinks it should be used (and that the NIH is wrong for waiting for more clinical trials). . It was not compatible with his position as CEO to continue taking a very public stance on the vaccines, Richard Char, M10s general counsel, told me. ICER, a non-profit known as the nations drug pricing watchdog, did a review of the evidence and determined that fluvoxamine evidence is superior to Molnupiravir. An approach that promised to democratize design may have done the opposite. Most doctors wont use it until NIH greenlights it, no matter what the science says. . 22, 2021, 9:00 a.m. Steve Kirsch , a former tech entrepreneur who earned a fortune worth up to $300 million, has been showcased on TrialSite a few times for his activity supporting the clinical development of repurposed drugs for COVID-19 treatments. are all super cheap, effective, and available without a prescription. In June, after CETFs advisory board resigned, Kirsch did a Facebook Live video with Zelenko and celebrity rehab coach Dr. Drew. Hes a genuinely good guy. This is what the Seftel trial at Golden Gate fields used. The NIH never did a risk benefit analysis of this drug. After two weeks (since it was a tight knit community, everyone could see what was happening to the two groups), every track worker who got sick with COVID, demanded the drug. Here is the latest version. Doctors are afraid that even with a 37-year safety record of this drug, that something will go terribly wrong and they will be blamed. That is when the phase 2 results were published. All the supporting observational studies were positive as well. Hes also made several videos and podcasts with Vladimir Zelenko, the conspiracy theorist doctor who convinced Trump to take hydroxychloroquine. Patients should be advised to limit/avoid the use of caffeine while on the drug since fluvoxamine extends the half life of caffeine (making you super wired). We could have saved a lot of lives. 4000fluvoxamine750 According to its founder, serial tech entrepreneur Steve Kirsch, CETF was started in April 2020 in order to fund. Fluvoxamine public data repository - Google Drive, On Cytokines, Fluvoxamine and COVID-19 Part 1, Jon-Emile S. Kenny MD[@heart_lung] You see, we have a kind of allergy to the past; its our national disease, and the very assurance with which you insist that the past is within the present is l, On Cytokines, Fluvoxamine and COVID-19 Part 2, Jon-Emile S. Kenny MD[@heart_lung] Apocalypse is played out now on a personal scale; it is not in the sky above us, but in our bed. -Mark Doty Introduction With a proposed pathway coupling patho, Effect of Fluvoxamine vs Placebo on Clinical Deterioration in Outpatients With Symptomatic COVID-19, This randomized trial compares the effects of fluvoxamine, a selective serotonin reuptake inhibitor with immunomodulatory effects vs placebo on a composite of dyspnea or pneumonia and oxygen desaturation among adult outpatients with polymerase chain reactionconfirmed mild coronavirus disease 2019 (, Prospective cohort of fluvoxamine for early treatment of COVID-19, Abstract. Its motivated out of his sense of keeping people safe and advancing health care.. Read More fluvoxamine The Fluvoxamine FAQ Drug researchers at Washington University in St. Louis reached out to Kirsch looking for $67,000 to finish a very smallbut placebo-controlledtrial. There were no studies reported out so far where fluvoxamine made things worse or neutral. Telling the truth, he tweeted. All can merit a fluvoxamine prescription based on traditional diagnoses. Thanks to the volumes of data and information provided by pharmaceutical companies and regulators, as well as large numbers of trials from independently funded research groups around the world, I now trust that theyre safe for the vast majority of adults. [NIH] doesnt want any of these treatments. They were all given the drug soon after symptoms and the placebo group was pure in that they were not taking any COVID drugs. Article about the rejection (Stat News) Article about the fluvoxamine rejection (The Verge) NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). And that is what has allowed Kirsch, and people like him, to become so influential. Stopping the meds will return you to your normal self. Once the Phase 2 result came out, it should have been embraced by doctors. The 50mg BID dose was quite effective, but it has to be started early (as soon as symptoms start). At the dosing for COVID (50mg BID x 14 days), there is a 1% chance of mild-nausea and because the dose is so low and the time it is taken is so short, and there are no psychotropic effects (which require more than 3 weeks of use; the psychotropic effects non-existent if you don't have depression or an anxiety disorder in the first place). You will be wired for 24 hours if you dont heed my advice. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. 12:45 AM . . (The ivermectin data are trash, Feinberg told me. The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. Although the average effect size is 100% with a p-value of <.0001, The Fisher exact test on the combined data suggests that there is a 95% chance that the effect size is at least a 75% reduction in hospitalization rate. Try refreshing this page and updating them one Skirsch.io traffic volume is 1,957 unique daily visitors and their 3,914 pageviews. Zero. 1991-1992 to 7.1% in 2001-2002. 19 In addition, several . The Wall Street Journal thinks it should be used (and that the NIH is wrong for waiting for more clinical trials). Now weve lost the high ground, Morris told me. . Its whether Merck can make a killing that matters. Always be self aware when using fluvoxamine. All have had a 100% success record in keeping their patients out of the hospital. ALWAYS check with your doctor and report any medications you are taking before or plan to take after you start taking fluvoxamine. Over the summer, the conflict reached his most recent startup, M10. With little government funding available for such work, Kirsch founded the Covid-19 Early Treatment Fund (CETF), putting in $1 million of his own money and bringing in donations from Silicon Valley luminaries: the CETF website lists the foundations of Marc Benioff and Elon Musk as donors. We should not wait for the Phase 3 RCT. Molnupiravir followed patients for only 30 days because they know the drug is dangerous. That trial has now been completed, and the researchers are analyzing their data. The NIH did nothing despite the fact the that NIH, FDA, CDC, and academic institutions participated in the panel, this is NOT about the science. Steve Kirsch was extremely helpful early on in the pandemic, stepping up to fund early treatment trials when the US government would not fund such studies, Boulware told me in an email. In a recent post, discussing claims Kirsch made during a three-minute comment at an FDA public forum, Morris wrote: In spite of many pages of writing and claims of over a dozen independent analyses verifying their results, their evidence falls far short of substantiating these dramatic conclusions, including a claim that vaccines have caused >250K excess deaths in the USA.. We are ignoring the advice of the KOL group and doing nothing. 1 hr ago. Comparison with molnupiravir. Here are my answers. Generally, at 50mg BID x 14, it is very tolerable as long as the patient is instructed to lay off the caffeine. Skirsch.io Steve Kirsch Home page Fluvoxamine, COVID, pandemic, . Has it really been 25 years, a whole quarter of a century? Soon after his appearance on the DarkHorse podcast, several partners of his most recent startup, M10, expressed concerns about the increasing extremism of Kirschs vaccine views. This advice is now outdated. Don't underestimate the virus. Fauci wants the vaccine to be the only option, Cliff Lane works for Fauci, and Cliff follows his orders. Kirsch IDeacon BJHuedo-Medina TBScoboria AMoore TJJohnson BT Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration. Talking to Kirsch is an exhausting experience. My crime? By March 2020, hed settled on the idea of searching for covid treatments in the pre-existing pharmacopeia. Quick Summary . But fear of trying something new prevents any doctor from giving this drug a try. All the supporting observational studies were positive as well. To protect M10 from my COVID-19 vaccination opinions, I will no longer post about my vaccination concerns here. The most stunning study of fluvoxamine ever done was at the Golden Gate Fields racetrack in November 2020, right after the WashU trial was published in JAMA. He was recently featured on 60 Minutes, . Have the drug on hand. To vet proposals, he recruited a powerhouse advisory board of prominent biologists, drug developers, and clinical researchers, led by world-renowned drug researcher Robert Siliciano of Johns Hopkins. About 10 minutes on the internet will show you those two gentlemen, who have appeared together, have been extensively fact checked for false or misleading claims or misuse of VAERS reporting and other data. Answer (1 of 2): Yes, In a preliminary study of COVID-19 patients with mild-to-moderate disease who were attempting to recover in their homes, researchers at Washington University School of Medicine in St. Louis have found that the drug fluvoxamine seems to prevent some of the most serious compli. Medicine isnt about saving lives anymore. That is when the phase 2 results were published. He says that Facebook took down one of his posts announcing his appearance on 60 Minutes. Every year, we pick the 10 technologies that matter the most right now. Seftel was able to duplicate the 100% protection from hospitalization and death in the treatment group, vs. a 12.5% hospitalization/death rate for the No treatment group. I have all of these on hand and I load up on vitamin D3 every day. But while this effort was praiseworthy, Kirsch's predilection for oversimplifying and exaggerating led him to mislead. The post read: "I will be featured on 60 Minutes this Sunday talking about fluvoxamine as an effective treatment for COVID-19 to prevent hospitalization and death. There is an executive summary below, but the most important thing is that top infectious disease docs who have looked at all the evidence (including the two clinical trial results) believe the effect size is 75% or more in reducing the hospitalization rate. To date, we have heard nothing suggesting the drug doesn't work or could be harmful. He retired at the largest pension in federal history. Sadly, doctors and public health officials refuse to instruct patients to seek early treatment. Early treatment with existing drugs is the fastest, most effective, and lowest. Its actually much harder to parse out a signal than if youre treating diabetes or cancer., In addition to the issues with fluvoxamine, advisors grew increasingly uncomfortable with Kirschs posts about ivermectin, which he has repeatedly claimed in blog posts and appearances in alternative media can be used together with fluvoxamine to prevent 100% of covid-19 deaths. Saving the world has been a theme of Kirschs life for years. We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. Steve Kirsch. Get your prescription in advance of getting COVID. Share this post. Do they sell it anywhere? All this was known back in January 2021 when a key opinion leader panel of experts from NIH, CDC, FDA, academia, and journal editors voted by over 2:1 to recommend that fluvoxamine be recommended to physicians to discuss with patients. This is the #1 ranked best answer to "COVID treatment" on Quora: Presentation on how fear of trying something new is what keeps us shutdown and leads to unnecessary loss of life: The Lenze fluvoxamine RCT that was published in JAMA on November 12, 2020 showed a 100% success rate in preventing hospitalization. So the drug had no chance of working (since there were no events), so the trial was stopped for futility, NOT because the drug doesnt work. He was recently featured on 60 Minutes which highlighted his . Entrepreneur Steve Kirsch who holds an early patent for the optical mouse decided to get involved in treating Covid. Ivermectin has been falsely promoted as a covid treatmentbut for those who use the drug legitimately, seeing it become a piece of anti-vaccine misinformation is disconcerting. Fluoxetine is just as effective. Those days are gone. of the 'intellectual dark web '" and allowed him to access a "large and receptive audience to his claims about a fluvoxamine conspiracy". Most recent articles first. This alone will give roughly a 50% effect size and explains why all of the the SSRIs are effective including those that do not activate the Sigma1 receptor (e.g., Paroxetine). During our first conversation, which turned into a multi-hour Zoom session, Kirsch paced through the rooms of his cavernous house with his phone held at chest level, rarely looking down at the camera. The drugs mechanisms of action were explained to the KOL panel which voted 2>1 in favor of fluvoxamine. After I ended the Zoom meeting, Satterfield called me to apologize for cutting us off. NIH is still unsure whether fluvoxamine should be used to treat COVID (article I did after the TOGETHER trial). But a panel of key opinion leaders from the NIH, CDC . Also, for people who cant tolerate fluvoxamine for whatever reason (nausea, jittery, etc), this is the alternative. The premise made sense: Most experts were predicting vaccines would take years, while finding helpful drugs with known safety profiles could shortcut the approval process. Fluvoxamine works on hospitalized patients too, but no US hospital will let you use it (sound familiar? Im sorry to sound so cynical. The paramedics will think you are on drugs. The sooner you start, the better the outcomes. In 2013, Johnson & Johnson paid $2.2 billion for its own kickback and fraud scandal, including a specific $400 million fine for its subsidiary Janssen, which manufactures the covid vaccine. Who knows, Morris replied. But they dont want their names used. Kirsch and his wife, Michele, fund a charitable foundation, which by 2007 had given $75 million to different causes. It is an amazing drug and is a very simple safe way to avoid long-haul COVID symptoms. I couldnt tell I was on the drug. See this. CETF was founded by entrepreneur and philanthropist Steve Kirsch, as a way to expedite the fight against COVID-19. Medicine today isnt about saving your life. Silence from the medical community. But the confusion provided a fertile breeding ground for skeptics. I've asked people, "there's a lot of evidence here it's not just a small phase 2 RCT. Enter the email address you signed up with and we'll email you a reset link. Here's why. Government agencies are ignoring the science. They rejected the drug for insufficient evidence just like they always do for ivermectin. Note that some of these articles are inaccurate. What happens when your prescription drug becomes the center of covid misinformation. CETF funded David Boulware's trials on hydroxychloroquine and the Phase 2 and Phase 3 fluvoxamine trials, among many other research projects. We should be making decisions now based on the evidence on the table today. It is perhaps the greatest unnecessary loss of life in American history. They never make things worse so are safe to try. I have never heard of a case it didn't work. Steve Kirsch is an inventor of the optimal mouse, a Silicon Valley millionaire, and an MIT alum (Class of '80). By Steve Kirsch Last updated: March 14, 2021 After I appeared on the60 Mi nut es story about fluvoxamine,I've received a lot of questions from people about how to treat COVID. Steve Kirsch: Vaccine Killing Millions, Treatments, VAERS, 5-Month Death Signal, Mystery Clots Embed 7.76K 31 'This Has Cost Millions Of Lives': Steve Kirsch On Suppression Of Repurposed Drugs And A Spike In Deaths 5 Months After Vaccine Rollout By Jan Jekielek American Thought Leaders / The Epoch Times November 24, 2022 Show more He started 7 high tech companies, two with billion dollar market caps. Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized study to prevent clinical deterioration of patients with mild coronavirus disease 2019 (COVID-19). Dr. Joe Ladapo wrote a brilliant op-ed in the Wall Street Journal, "Too much caution is killing COVID patients." Waiting months for the phase 3 trial to complete is nuts. I fully expected both organizations to do absolutely nothing. It could do nothing. Ive talked to doctors who are extremely familiar with the drug and all the trial results and they would prescribe it to their patients. There may be a depression of libido while on drug, but since the drug is taken on acute basis, this is only temporary and it reverses once the drug is stopped. Vitamin D, NAC, betadine, aspirin, and Nigella sativa are all super cheap, effective, and available without a prescription. Everyone is stunned, but nobody is surprised. How I recommend people treat COVID and the fascinating backstory of how fluvoxamine was discovered. Kirsch is a serial entrepreneur who has spent decades pitching the next big thing, whether optical mice (Mouse Systems), document processing (FrameMaker), search engines (Infoseek), digital. His latest startup, M10, is a spin-off of a spin-off that sells a blockchain for banks. I didnt intend to spend a lot of time on Steve in particular, but that video was so influential.. In every case we are aware of, the drug was successful in reversing COVID symptoms, generally in 3 days or less. We don't know why the NIH panel is ignoring fluvoxamine and we aren't allowed to find out. Compulsive fiddling with your mask? 533. This drug can save your life but you have to ask for it! Infoseek lost out to Yahoo; it had a chance to grow bigger, but it didn't. Im not going to make the same mistake again.. After several failed attempts to stop the progression of his disease, he designed his own protocol for chemotherapy and doctor-shopped to find an oncologist who would give it to him. sorry about that. Jeffrey Morris, director of biostatistics at the University of Pennsylvania Perelman School of Medicine, has made debunking Kirschs claims something of a hobby. The study was also featured on 60 Minutes. See this Wall Street Journal op-ed. including the very promising Fluvoxamine. Why not fluvoxamine? Fluvoxamine, COVID, pandemic, . He might be a good snake oil salesman., I experienced this myself when, on one call, we discussed several studies.

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